TargetMol

PERK-IN-4

Product Code:
 
TAR-T38732
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38732-1mg1mg£118.00
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Quantity:
TAR-T38732-5mg5mg£189.00
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Quantity:
TAR-T38732-10mg10mg£254.00
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Quantity:
TAR-T38732-25mg25mg£414.00
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Quantity:
TAR-T38732-50mg50mg£581.00
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Quantity:
TAR-T38732-100mg100mg£783.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PERK-IN-4 is a potent and selective PERK (protein kinase R (PKR)-like endoplasmic reticulum kinase) inhibitor with an IC 50 of 0.3 nM. PERK is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states.
CAS:
1337531-89-1
Formula:
0
Molecular Weight:
0
Pathway:
Apoptosis
Purity:
0.98
SMILES:
0
Target:
PERK

References

Axten JM, et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem. 2012;55(16):7193-7207.