TargetMol

ONO-8430506

Product Code:
 
TAR-T38759
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38759-1mg1mg£322.00
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Quantity:
TAR-T38759-5mg5mg£683.00
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Quantity:
TAR-T38759-1mL1 mL * 10 mM (in DMSO)£787.00
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TAR-T38759-10mg10mg£930.00
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Quantity:
TAR-T38759-25mg25mg£1,348.00
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Quantity:
TAR-T38759-50mg50mg£1,781.00
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Quantity:
TAR-T38759-100mg100mg£2,392.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ONO-8430506 is an orally bioavailable and potent autotaxin (ATX)/ENPP2 inhibitor with the IC 90 of 100 nM for ATX activity in mouse plasma.
CAS:
1354805-08-5
Formula:
0
Molecular Weight:
0
Pathway:
Metabolism
Purity:
0.98
SMILES:
0
Target:
PDE

References

Hiroshi Saga, et al. A novel highly potent autotaxin/ENPP2 inhibitor produces prolonged decreases in plasma lysophosphatidic acid formation in vivo and regulates urethral tension. PLoS One. 2014;9(4):e93230. Yuzo Iwaki, et al. ONO-8430506: A Novel Autotaxin Inhibitor That Enhances the Antitumor Effect of Paclitaxel in a Breast Cancer Model. ACS Med Chem Lett. 2020;11(6):1335-1341. Matthew G K Benesch, et al. Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice. FASEB J. 2014;28(6):2655-2666.