TargetMol

Calpain Inhibitor-1

Product Code:
 
TAR-T38931
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38931-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Calpain Inhibitor-1 (compound 36) is a potent and selective cysteine protease calpain 1 (Cal1) inhibitor ( IC 50 =100 nM; K i =2.89 μM).
CAS:
1448429-06-8
Formula:
C19H17FN6O5S
Molecular Weight:
460.44
Purity:
0.98
SMILES:
OC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](Cc1cscn1)C(=O)NCc1cn(nn1)-c1ccc(F)cc1

References

Schiefer IT, Tapadar S, Litosh V, et al. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. J Med Chem. 2013;56(15):6054-6068.