TargetMol

Uzansertib

Product Code:
 
TAR-T39090
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39090-5mg5mg£850.00
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Further Information

Bioactivity:
Uzansertib (INCB053914) is an orally active, ATP-competitive pan- PIM kinase inhibitor with IC 50 s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib has broad anti-proliferative activity against a variety of hematologic tumor cell lines.
CAS:
1620012-39-6
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Koblish H, et al. Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies. PLoS One. 2018 Jun 21;13(6):e0199108.