TargetMol

β-catenin-IN-37

Product Code:
 
TAR-T39200
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39200-5mg5mg£850.00
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Further Information

Bioactivity:
β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-catenin-IN-37 inhibits canonical Wnt signaling and the growth of colorectal cancer cells SW480 and HCT116 with the IC 50 values of 20 μM and 31 μM, respectively.
CAS:
1783856-40-5
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Catrow JL, et al. Discovery of Selective Small-Molecule Inhibitors for the ?-Catenin/T-Cell Factor Protein-Protein Interaction through the Optimization of the Acyl Hydrazone Moiety. J Med Chem. 2015;58(11):4678-4692.