TargetMol

Jatrorrhizine

Product Code:
 
TAR-T3933
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3933-5mg5mg£111.00
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TAR-T3933-10mg10mg£132.00
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TAR-T3933-25mg25mg£180.00
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TAR-T3933-50mg50mg£230.00
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TAR-T3933-100mg100mg£310.00
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Further Information

Bioactivity:
Jatrorrhizine is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits monoamine oxidase (IC50 4 micromolar for MAO-A and 62 for MAO-B).
CAS:
3621-38-3
Formula:
C20H20NO4
Molecular Weight:
338.382
Pathway:
Metabolism; Microbiology/Virology; Neuroscience; GPCR/G Protein
Purity:
0.9906
SMILES:
COc1cc-2c(CC[n+]3cc4c(OC)c(OC)ccc4cc-23)cc1O
Target:
MAO; 5-HT Receptor; Antibacterial; AChE

References

Li J1, Li J, Jiao Y, Dong C.Spectroscopic analysis and molecular modeling on the interaction of jatrorrhizine with human serum albumin (HSA).Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jan 24;118:48-54. Wu H1, He K2, Wang Y2, et al.The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis.Phytomedicine. 2014 Sep 25;21(11):1373-81. Mi R1, Hu YJ, Fan XY, Ouyang Y, Bai AM.Exploring the site-selective binding of jatrorrhizine to human serum albumin: spectroscopic and molecular modeling approaches.Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jan 3;117:163-9.