TargetMol

AR7

Product Code:
 
TAR-T3955
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3955-5mg5mg£121.00
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Quantity:
TAR-T3955-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T3955-10mg10mg£148.00
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TAR-T3955-25mg25mg£242.00
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TAR-T3955-50mg50mg£349.00
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Quantity:
TAR-T3955-100mg100mg£535.00
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Quantity:
TAR-T3955-200mg200mg£711.00
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Quantity:
TAR-T3955-500mg500mg£1,050.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AR7 is a retinoic acid receptor α (RARα) antagonist.
CAS:
80306-38-3
Formula:
C15H12ClNO
Molecular Weight:
257.72
Pathway:
Metabolism
Purity:
0.9952
SMILES:
Cc1ccc(cc1)C1=Nc2ccc(Cl)cc2OC1
Target:
Retinoid Receptor

References

Xiong Q, Sun H, Xing W, et al.WDR45 mutation dysregulates iron homeostasis by promoting the chaperone-mediated autophagic degradation of ferritin heavy chain in an ER stress/p38 dependent mechanism.Free Radical Biology and Medicine.2023 Jiang S, Wang X, He Y, et al. Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis[J]. Cell Death & Disease. 2021, 12(5): 1-12. Jiang S, Wang X, He Y, et al. Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis. Cell Death & Disease. 2021, 12(5): 1-12. Anguiano J, et al. Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives. Nat Chem Biol. 2013 Jun;9(6):374-82.