TargetMol

MS33

Product Code:
 
TAR-T39975
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39975-5mg5mg£850.00
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Further Information

Bioactivity:
MS33 is a potent WDR5 degrader, with K d s of 870 nM and 120 nM for VCB and WDR5 , respectively. MS33 induces WDR5 degradation in an E3 ligase VHL, and proteasome-dependent manner. MS33 can be used for the research of acute myeloid leukemia.
CAS:
2407449-11-8
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Yu X, et, al. A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med. 2021 Sep 29;13(613):eabj1578.