TargetMol

6'-GNTI dihydrochloride

Product Code:
 
TAR-T39988
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39988-1mg1mg£352.00
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TAR-T39988-5mg5mg£748.00
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TAR-T39988-10mg10mg£1,002.00
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TAR-T39988-25mg25mg£1,460.00
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Quantity:
TAR-T39988-50mg50mg£1,942.00
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Further Information

Bioactivity:
6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons.
CAS:
2410327-94-3
Formula:
0
Molecular Weight:
0
Pathway:
PI3K/Akt/mTOR signaling|Endocrinology/Hormones|Neuroscience|Cytoskeletal Signaling|GPCR/G Protein
Purity:
0.98
SMILES:
0
Target:
Opioid Receptor|Akt

References

Schmid CL, et al. Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at ?-opioid receptors in striatal neurons. J Biol Chem. 2013;288(31):22387-22398.