TargetMol

IACS-15414

Product Code:
 
TAR-T39999
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39999-5mg5mg£265.00
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Further Information

Bioactivity:
IACS-15414 is a potent and orally bioavailable SHP2 inhibitor with an IC 50 value of 122 nM.
CAS:
2411321-29-2
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Czako B, et al. Discovery of 6-[(3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor. J Med Chem. 2021 Oct 28;64(20):15141-15169.