TargetMol

Sodium Camptothecin

Product Code:
 
TAR-T40179
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T40179-10mg10mg£102.00
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TAR-T40179-25mg25mg£122.00
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TAR-T40179-50mg50mg£146.00
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TAR-T40179-100mg100mg£182.00
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This product comes from: United States.
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Further Information

Bioactivity:
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.
CAS:
25387-67-1
Formula:
C20H17N2NaO5
Molecular Weight:
388.355
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
[Na+].CCC(O)(C([O-])=O)c1cc2-c3nc4ccccc4cc3Cn2c(=O)c1CO
Target:
DNA/RNA Synthesis

References

R S Wu, et al. Ribosome formation is blocked by camptothecin, a reversible inhibitor of RNA synthesis. Proc Natl Acad Sci U S A. 1971 Dec;68(12):3009-14. M S Horwitz, et al. Camptothecin: mechanism of inhibition of adenovirus formation. Virology. 1972 Jun;48(3):690-8