TargetMol

AR-M 1000390 hydrochloride

Product Code:
 
TAR-T4236
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T4236-5mg5mg£122.00
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TAR-T4236-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T4236-10mg10mg£156.00
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TAR-T4236-25mg25mg£246.00
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TAR-T4236-50mg50mg£389.00
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TAR-T4236-100mg100mg£548.00
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Further Information

Bioactivity:
AR-M 1000390 (hydrochloride), also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.
CAS:
209808-47-9
Formula:
C23H29ClN2O
Molecular Weight:
384.95
Pathway:
GPCR/G Protein; Neuroscience; Endocrinology/Hormones
Purity:
0.9968
SMILES:
Cl.CCN(CC)C(=O)c1ccc(cc1)C(=C1CCNCC1)c1ccccc1
Target:
Opioid Receptor

References

Marie N,etal.Pharmacological characterization of AR-M1000390 at human delta opioid receptors.Life Sci. 2003 Aug 15;73(13):1691-704. Pradhan AA,etal.Ligand-directed trafficking of the ?-opioid receptor in vivo: two paths toward analgesic tolerance.J Neurosci. 2010 Dec 8;30(49):16459-68.