TargetMol

Syk Inhibitor II

Product Code:
 
TAR-T4348
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4348-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T4348-5mg5mg£124.00
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TAR-T4348-10mg10mg£172.00
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TAR-T4348-50mg50mg£334.00
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Further Information

Bioactivity:
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
CAS:
726695-51-8
Formula:
C14H15F3N6O
Molecular Weight:
340.31
Pathway:
Tyrosine Kinase/Adaptors; Neuroscience; GPCR/G Protein; Angiogenesis
Purity:
0.9852
SMILES:
NCCNc1ncc(C(N)=O)c(Nc2cccc(c2)C(F)(F)F)n1
Target:
5-HT Receptor; Syk

References

Hisamichi H,etal.Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives.Bioorg Med Chem. 2005 Aug 15;13(16):4936-51.