TargetMol

Pipequaline

Product Code:
 
TAR-T4655
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4655-5mg5mg£104.00
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TAR-T4655-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T4655-25mg25mg£172.00
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TAR-T4655-50mg50mg£258.00
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TAR-T4655-100mg100mg£396.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.
CAS:
77472-98-1
Formula:
C22H24N2
Molecular Weight:
316.448
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.98
SMILES:
C(Cc1cc(nc2ccccc12)-c1ccccc1)C1CCNCC1
Target:
GABA Receptor

References

Essassi D, et al. Pipequaline transport from blood to brain and liver: role of plasma protein-bound drug. J Pharm Pharmacol. 1989 Sep;41(9):595-600. Debonnel G, et al. Pipequaline acts as a partial agonist of benzodiazepine receptors: an electrophysiological study in the hippocampus of the rat. Neuropharmacology. 1987 Sep;26(9):1337-42. File SE., et al. Sedative effects of PK 9084 and PK 8165, alone and in combination with chlordiazepoxide. Br J Pharmacol. 1983 May;79(1):219-23.