TargetMol

Daphnoretin

Product Code:
 
TAR-T4S1335
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S1335-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T4S1335-20mg20mg£151.00
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Further Information

Bioactivity:
1. Daphnoretin has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way. 3. Daphnoretin causes death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.
CAS:
2034-69-7
Formula:
C19H12O7
Molecular Weight:
352.298
Pathway:
Chromatin/Epigenetic; Microbiology/Virology; Apoptosis; Proteases/Proteasome; Cytoskeletal Signaling
Purity:
0.998
SMILES:
COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O
Target:
Influenza Virus; Caspase; PKC

References

Jiang H , Wu Z , Bai X , et al. Effect of daphnoretin on the proliferation and apoptosis of A549 lung cancer cells in vitro[J]. Oncology Letters, 2014, 8(3):1139---1142.