TargetMol

Toltrazuril (sulfone)

Product Code:
 
TAR-T5052
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5052-10mg10mg£107.00
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TAR-T5052-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T5052-25mg25mg£128.00
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TAR-T5052-50mg50mg£148.00
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Quantity:
TAR-T5052-100mg100mg£166.00
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This product comes from: United States.
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Further Information

Bioactivity:
Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites.
CAS:
69004-04-2
Formula:
C18H14F3N3O6S
Molecular Weight:
457.38
Pathway:
Microbiology/Virology
Purity:
0.9942
SMILES:
Cc1cc(ccc1Oc1ccc(cc1)S(=O)(=O)C(F)(F)F)-n1c(=O)[nH]c(=O)n(C)c1=O
Target:
Parasite

References

Dirikolu L, Karpiesiuk W, Lehner AF, Hughes C, Granstrom DE, Tobin T. Synthesis and detection of toltrazuril sulfone and its pharmacokinetics in horses following administration in dimethylsulfoxide. J Vet Pharmacol Ther. 2009 Aug;32(4):368-78. Kaduk J A, Gates-Rector S, Blanton T N. Crystal structure of ponazuril, C18H14F3N3O6S. Powder Diffraction. 2022: 1-5. Pharmacokinetics of ponazuril after oral administration to healthy Ilamas (Lama glama) By Prado, Maria E.; Ryman, Josiah T.; Boileau, Melanie J.; Martin-Jimenez, Tomas; Meibohm, Bernd From American Journal of Veterinary Research (2011), 72(10), 1386-1389 Dirikolu L, Yohn R, Garrett EF, Chakkath T, Ferguson DC. Detection, quantifications and pharmacokinetics of toltrazuril sulfone (Ponazuril) in cattle. J Vet Pharmacol Ther. 2009 Jun;32(3):280-8. Dirikolu L, Karpiesiuk W, Lehner AF, Tobin T. Toltrazuril sulfone sodium salt: synthesis, analytical detection, and pharmacokinetics in the horse. J Vet Pharmacol Ther. 2012 Jun;35(3):265-74. Lim JH, Kim MS, Hwang YH, Song IB, Park BK, Yun HI. Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs. J Vet Med Sci. 2010 Aug;72(8):1085-7.