TargetMol

Glecaprevir

Product Code:
 
TAR-T5126
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T5126-2mg2mg£96.00
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TAR-T5126-5mg5mg£112.00
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TAR-T5126-1mL1 mL * 10 mM (in DMSO)£129.00
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TAR-T5126-10mg10mg£132.00
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TAR-T5126-25mg25mg£197.00
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TAR-T5126-50mg50mg£302.00
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TAR-T5126-100mg100mg£430.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).
CAS:
1365970-03-1
Formula:
C38H46F4N6O9S
Molecular Weight:
838.87
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.9916
SMILES:
CC(C)(C)[C@@H]1NC(=O)O[C@@H]2CCC[C@H]2OCC=CC(F)(F)c2nc3ccccc3nc2O[C@@H]2C[C@H](N(C2)C1=O)C(=O)N[C@@]1(C[C@H]1C(F)F)C(=O)NS(=O)(=O)C1(C)CC1
Target:
HCV Protease; SARS-CoV

References

Lawitz EJ, et al. Potent Antiviral Activities of the Direct-Acting Antivirals ABT-493 and ABT-530 with Three-Day Monotherapy for Hepatitis C Virus Genotype 1 Infection. Antimicrob Agents Chemother. 2015 Dec 28;60(3):1546-55. Ng TI, et al. In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir. Antimicrob Agents Chemother. 2017 Oct 30. pii: AAC.201620-17.