TargetMol

CZC-25146 hydrochloride

Product Code:
 
TAR-T5139
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5139-1mg1mg£111.00
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TAR-T5139-5mg5mg£160.00
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TAR-T5139-10mg10mg£230.00
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TAR-T5139-25mg25mg£335.00
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TAR-T5139-50mg50mg£466.00
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TAR-T5139-100mg100mg£646.00
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This product comes from: United States.
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Further Information

Bioactivity:
CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.
CAS:
1330003-04-7
Formula:
C22H26ClFN6O4S
Molecular Weight:
525
Pathway:
Autophagy
Purity:
0.9906
SMILES:
Cl.COc1cc(ccc1Nc1ncc(F)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1
Target:
LRRK2

References

Ramsden N, et al. Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons. ACS Chem Biol. 2011 Oct 21;6(10):1021-8.