TargetMol

KHS101 hydrochloride

Product Code:
 
TAR-T5170
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5170-1mg1mg£99.00
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TAR-T5170-2mg2mg£112.00
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TAR-T5170-5mg5mg£138.00
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TAR-T5170-1mL1 mL * 10 mM (in DMSO)£146.00
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TAR-T5170-10mg10mg£173.00
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TAR-T5170-25mg25mg£282.00
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TAR-T5170-50mg50mg£425.00
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TAR-T5170-100mg100mg£592.00
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This product comes from: United States.
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Further Information

Bioactivity:
KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.
CAS:
1784282-12-7
Formula:
C18H22ClN5S
Molecular Weight:
375.92
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; Cytoskeletal Signaling
Purity:
0.996
SMILES:
Cl.CC(C)CNc1ccnc(NCc2csc(n2)-c2ccccc2)n1
Target:
FGFR; Microtubule Associated

References

Zhou DS, et al. TACC3 promotes stemness and is a potential therapeutic target in hepatocellular carcinoma. Oncotarget. 2015 Sep 15;6(27):24163-77. Wurdak H, et al. A small molecule accelerates neuronal differentiation in the adult rat. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16542-7. Polson ES, et al. KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice. Sci Transl Med. 2018 Aug 15;10(454). pii: eaar2718.