TargetMol

Omadacycline mesylate

Product Code:
 
TAR-T5189L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T5189L-5mg5mg£850.00
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Further Information

Bioactivity:
Omadacycline is an aminomethylcycline antibiotic. Omadacycline demonstrated net cidal activity in relation to the initial burden against four strains of Streptococcus pneumoniae.
CAS:
1196800-40-4
Formula:
C30H44N4O10S
Molecular Weight:
652.76
Purity:
0.98
SMILES:
CS(O)(=O)=O.[H][C@@]12Cc3c(cc(CNCC(C)(C)C)c(O)c3C(O)=C1C(=O)[C@]1(O)C(O)=C(C(N)=O)C(=O)[C@@H](N(C)C)[C@]1([H])C2)N(C)C

References

Lepak AJ, Zhao M, Marchillo K, VanHecker J, Andes DR. In Vivo Pharmacodynamic Evaluation of Omadacycline (PTK 0796) against Streptococcus pneumoniae in the Murine Pneumonia Model. Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02368-16. doi: 10.1128/AAC.02368-16. Print 2017 May. PubMed PMID: 28193651; PubMed Central PMCID: PMC5404567. Swathi CH, Chikala R, Ratnakar KS, Sritharan V. A structural, epidemiological & genetic overview of Klebsiella pneumoniae carbapenemases (KPCs). Indian J Med Res. 2016 Jul;144(1):21-31. doi: 10.4103/0971-5916.193279. Review. PubMed PMID: 27834322; PubMed Central PMCID: PMC5116894. T?r?k ME, Chapman AL, Lessing MP, Sanderson F, Seaton RA. Outpatient parenteral antimicrobial therapy: Recent developments and future prospects. Curr Opin Investig Drugs. 2010 Aug;11(8):929-39. Review. PubMed PMID: 20721835. Waites KB, Crabb DM, Liu Y, Duffy LB. In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7502-7504. Print 2016 Dec. PubMed PMID: 27671057; PubMed Central PMCID: PMC5119036.