TargetMol

BIBF0775

Product Code:
 
TAR-T5197
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5197-1mg1mg£123.00
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TAR-T5197-5mg5mg£191.00
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TAR-T5197-1mL1 mL * 10 mM (in DMSO)£201.00
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TAR-T5197-10mg10mg£256.00
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TAR-T5197-25mg25mg£374.00
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TAR-T5197-50mg50mg£497.00
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TAR-T5197-100mg100mg£687.00
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Quantity:
TAR-T5197-500mg500mg£1,340.00
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Further Information

Bioactivity:
BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
CAS:
334951-90-5
Formula:
C31H34N4O2
Molecular Weight:
494.639
Pathway:
Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
Purity:
0.9945
SMILES:
CCN(C)C(=O)c1ccc2C(=C(Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)C(=O)Nc2c1
Target:
ALK; TGF-beta/Smad

References

Roth GJ, et al. Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor ? receptor I (TGF?RI). J Med Chem. 2010 Oct 28;53(20):7287-95.