TargetMol

3-Chloro-L-Tyrosine

Product Code:
 
TAR-T5280
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5280-250mg250mg£104.00
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Further Information

Bioactivity:
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular, myeloperoxidase halogenates tyrosine residues in plasma proteins and generates 3-chlorotyrosine (CY). The detection of free chlorotyrosine in blood or urine arises from the degradation of these chlorinated proteins. CY concentrations may be useful for monitoring the activation of neutrophils in asthmatic patients.
CAS:
7423-93-0
Formula:
C9H10ClNO3
Molecular Weight:
215.63
Pathway:
Metabolism;
Purity:
0.9895
SMILES:
N[C@@H](Cc1ccc(O)c(Cl)c1)C(O)=O
Target:
Endogenous Metabolite

References

Hazen SL, et al. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest. 1997 May 1;99(9):2075-81.