TargetMol

Bepridil hydrochloride

Product Code:
 
TAR-T5391
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5391-5mg5mg£103.00
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TAR-T5391-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T5391-10mg10mg£114.00
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TAR-T5391-25mg25mg£149.00
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TAR-T5391-50mg50mg£179.00
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TAR-T5391-100mg100mg£222.00
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This product comes from: United States.
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Further Information

Bioactivity:
Bepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels.
CAS:
68099-86-5
Formula:
C24H35ClN2O
Molecular Weight:
403.01
Pathway:
Metabolism; Membrane transporter/Ion channel
Purity:
0.9945
SMILES:
Cl.CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
Target:
Calcium Channel

References

Flaim SF, et al. Effects of bepridil hydrochloride on cardiocirculatory dynamics, coronary vascular resistance, and cardiac output distribution in normal, conscious rats. J Cardiovasc Pharmacol. 1988 Mar;11(3):363-72. Li Y, et al. Bepridil blunts the shortening of action potential duration caused by metabolic inhibition via blockade of ATP-sensitive K(+) channels and Na(+)-activated K(+) channels. J Pharmacol Exp Ther. 1999 Nov;291(2):562-8. Qiu M, Li Z, Chen Y, et al. Tolcapone Potently Inhibits Seminal Amyloid Fibrils Formation and Blocks Entry of Ebola Pseudoviruses. Frontiers in Microbiology. 2020, 11: 504. Qiu M, Li Z, Chen Y, et al. Tolcapone Potently Inhibits Seminal Amyloid Fibrils Formation and Blocks Entry of Ebola Pseudoviruses. Frontiers in Microbiology. 2020, 11: 504