TargetMol

Cycloguanil

Product Code:
 
TAR-T5420L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T5420L-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T5420L-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T5420L-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Cycloguanil is an antimalarial.
CAS:
516-21-2
Formula:
C11H14ClN5
Molecular Weight:
251.72
Purity:
0.98
SMILES:
CC1(C)N=C(N)N=C(N)N1C2=CC=C(Cl)C=C2

References

Adane L, Bharatam PV. 3D-QSAR analysis of cycloguanil derivatives as inhibitors of A16V + S108T mutant Plasmodium falciparum dihydrofolate reductase enzyme. J Mol Graph Model. 2009 Nov;28(4):357-67. doi: 10.1016/j.jmgm.2009.09.001. Epub 2009 Sep 6. PubMed PMID: 19796975. Sivaprakasam P, Tosso PN, Doerksen RJ. Structure-activity relationship and comparative docking studies for cycloguanil analogs as PfDHFR-TS inhibitors. J Chem Inf Model. 2009 Jul;49(7):1787-96. doi: 10.1021/ci9000663. PubMed PMID: 19588935; PubMed Central PMCID: PMC2771436. Basak SC, Mills D. Quantitative structure-activity relationships for cycloguanil analogs as PfDHFR inhibitors using mathematical molecular descriptors. SAR QSAR Environ Res. 2010 Apr;21(3-4):215-29. doi: 10.1080/10629361003770951. PubMed PMID: 20544548. Thapar MM, Gupta S, Spindler C, Wernsdorfer WH, Bj?rkman A. Pharmacodynamic interactions among atovaquone, proguanil and cycloguanil against Plasmodium falciparum in vitro. Trans R Soc Trop Med Hyg. 2003 May-Jun;97(3):331-7. PubMed PMID: 15228254.