TargetMol

SIS17

Product Code:
 
TAR-T5631
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5631-5mg5mg£118.00
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TAR-T5631-10mg10mg£149.00
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TAR-T5631-25mg25mg£222.00
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TAR-T5631-50mg50mg£329.00
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Quantity:
TAR-T5631-100mg100mg£483.00
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Further Information

Bioactivity:
SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.
CAS:
2374313-54-7
Formula:
C21H38N2OS
Molecular Weight:
366.61
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCCNNC(=O)c1cccs1
Target:
HDAC

References

Son S I , Cao J , Zhu C L , et al. Activity-Guided Design of HDAC11-Specific Inhibitors[J]. ACS Chemical Biology, 2019, 14(7):1393-1397.