TargetMol

TRPM8 antagonist 2

Product Code:
 
TAR-T5698
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5698-1mg1mg£98.00
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TAR-T5698-5mg5mg£132.00
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TAR-T5698-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T5698-10mg10mg£172.00
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TAR-T5698-25mg25mg£245.00
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TAR-T5698-50mg50mg£346.00
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TAR-T5698-100mg100mg£529.00
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Further Information

Bioactivity:
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.
CAS:
259674-19-6
Formula:
C26H26N2O2
Molecular Weight:
398.506
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
COC(=O)[C@H](Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1
Target:
TRP/TRPV Channel

References

Alessia B , Nunzio I , Carmine O , et al. Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity[J]. Journal of Medicinal Chemistry, 2018:acs.jmedchem.8b00545-.