TargetMol

Sesamolin

Product Code:
 
TAR-T5S2283
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S2283-1mg1mg£95.00
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TAR-T5S2283-5mg5mg£128.00
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TAR-T5S2283-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T5S2283-10mg10mg£173.00
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TAR-T5S2283-25mg25mg£246.00
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TAR-T5S2283-50mg50mg£332.00
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TAR-T5S2283-100mg100mg£461.00
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Further Information

Bioactivity:
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can significantly attenuate the excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells.
CAS:
526-07-8
Formula:
C20H18O7
Molecular Weight:
370.357
Pathway:
Proteases/Proteasome; Apoptosis; MAPK
Purity:
0.9889
SMILES:
C1Oc2ccc(O[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c3ccc4OCOc4c3)cc2O1
Target:
p38 MAPK; Caspase; JNK

References

Cheng F C , Jinn T R , Hou R C W , et al. Neuroprotective Effects of Sesamin and Sesamolin on Gerbil Brain in Cerebral Ischemia[J]. International Journal of Biomedical Science Ijbs, 2006, 2(3):284-288.