TargetMol

Thiamet G

Product Code:
 
TAR-T6056
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6056-2mg2mg£100.00
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TAR-T6056-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T6056-5mg5mg£116.00
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TAR-T6056-10mg10mg£146.00
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TAR-T6056-25mg25mg£230.00
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TAR-T6056-50mg50mg£360.00
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TAR-T6056-100mg100mg£502.00
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TAR-T6056-500mg500mg£1,026.00
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This product comes from: United States.
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Further Information

Bioactivity:
Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal ?hexosaminidase.
CAS:
1009816-48-1
Formula:
C9H16N2O4S
Molecular Weight:
248.3
Pathway:
Autophagy;
Purity:
0.9976
SMILES:
[H][C@]12O[C@H](CO)[C@@H](O)[C@H](O)[C@@]1([H])N=C(NCC)S2
Target:
Autophagy

References

Liu R, Liu Y, Zhang W, et al.PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma.Genes & Diseases.2023: 101114. Andr?s-Berg?s J, et al. J Biol Chem. 2012 Sep 28;287(40):33615-28. Goldberg H, et al. Am J Physiol Endocrinol Metab. 2011, 301(4), E713-726. Tan EP, et al. J Biol Chem. 2013, 288(38), 27085-27099. Yuzwa SA, et al. Nat Chem Biol. 2008, 4(8), 483-490.