TargetMol

Parbendazole

Product Code:
 
TAR-T6071
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6071-10mg10mg£107.00
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TAR-T6071-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6071-25mg25mg£128.00
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TAR-T6071-50mg50mg£149.00
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TAR-T6071-100mg100mg£209.00
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TAR-T6071-200mg200mg£277.00
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Further Information

Bioactivity:
Parbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
CAS:
14255-87-9
Formula:
C13H17N3O2
Molecular Weight:
247.298
Pathway:
Cytoskeletal Signaling; Microbiology/Virology
Purity:
0.98
SMILES:
CCCCc1ccc2[nH]c(NC(=O)OC)nc2c1
Target:
Microtubule Associated; Parasite

References

Havercroft J C , Quinlan R A , Gull K . Binding of parbendazole to tubulin and its influence on microtubules in tissue-culture cells as revealed by immunofluorescence microscopy[J]. Journal of Cell Science, 1981, 49(6):195. Lo Y C , Senese S , France B , et al. Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential[J]. Scientific Reports, 2017, 7(1):11261.