TargetMol

Cerdulatinib hydrochloride

Product Code:
 
TAR-T6104
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T6104-1mg1mg£100.00
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TAR-T6104-5mg5mg£140.00
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TAR-T6104-1mL1 mL * 10 mM (in DMSO)£144.00
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TAR-T6104-10mg10mg£164.00
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TAR-T6104-25mg25mg£250.00
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TAR-T6104-50mg50mg£386.00
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TAR-T6104-100mg100mg£540.00
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TAR-T6104-500mg500mg£1,091.00
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Further Information

Bioactivity:
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
CAS:
1369761-01-2
Formula:
C20H28ClN7O3S
Molecular Weight:
482
Pathway:
Chromatin/Epigenetic; Angiogenesis; MAPK; Tyrosine Kinase/Adaptors; Stem Cells; JAK/STAT signaling
Purity:
0.98
SMILES:
Cl.CCS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Target:
MLK; c-Fms; Tyrosine Kinases; Hippo pathway; JAK; Syk

References

Coffey G, J Pharmacol Exp Ther. 2014, 351(3), 538-548.