TargetMol

ZM39923 hydrochloride

Product Code:
 
TAR-T6145
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6145-5mg5mg£114.00
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Quantity:
TAR-T6145-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T6145-10mg10mg£148.00
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TAR-T6145-25mg25mg£214.00
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TAR-T6145-50mg50mg£333.00
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Quantity:
TAR-T6145-100mg100mg£462.00
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This product comes from: United States.
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Further Information

Bioactivity:
ZM 39923 HCl is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
CAS:
1021868-92-7
Formula:
C23H26ClNO
Molecular Weight:
367.92
Pathway:
Stem Cells; JAK/STAT signaling; Tyrosine Kinase/Adaptors; Angiogenesis; ; Chromatin/Epigenetic
Purity:
0.9805
SMILES:
Cl.CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc1ccccc1
Target:
EGFR; JAK

References

Lai TS, et al. Chem Biol, 2008, 15(9), 969-978. Brown GR, et al. Bioorg Med Chem Lett. 2000, 10(6), 575-579.