TargetMol

Combretastatin A4

Product Code:
 
TAR-T6212
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6212-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6212-20mg20mg£111.00
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Further Information

Bioactivity:
Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).
CAS:
117048-59-6
Formula:
C18H20O5
Molecular Weight:
316.353
Pathway:
Cytoskeletal Signaling
Purity:
0.9981
SMILES:
COc1ccc(C=C/c2cc(OC)c(OC)c(OC)c2)cc1O
Target:
Microtubule Associated

References

Fruytier AC, et al. NMR Biomed. 2014, 27(11), 1403-1412. Signoretto E, et al. Stimulation of Eryptosis by Combretastatin A4 Phosphate Disodium (CA4P). Cell Physiol Biochem. 2016;38(3):969-81 Tochinai R, et al. Combretastatin A4 disodium phosphate-induced myocardial injury. J Toxicol Pathol. 2016 Jul;29(3):163-71. Colliez F, et al. Magn Reson Med. 2015, doi: 10.1002/mrm.25642. Zheng S, et al. J Med Chem. 2014, 57(8), 3369-3381.