TargetMol

Dizocilpine

Product Code:
 
TAR-T6259
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6259-5mg5mg£116.00
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Quantity:
TAR-T6259-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T6259-10mg10mg£140.00
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TAR-T6259-25mg25mg£193.00
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Quantity:
TAR-T6259-50mg50mg£273.00
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Quantity:
TAR-T6259-100mg100mg£396.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
MK-801 (Dizocilpine) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
CAS:
77086-21-6
Formula:
C16H15N
Molecular Weight:
221.303
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9985
SMILES:
C[C@]12N[C@H](Cc3ccccc13)c1ccccc21
Target:
NMDAR; iGluR

References

Wang M, Liang X, Zhang Q, et al. Homocysteine can aggravate depressive like behaviors in a middle cerebral artery occlusion/reperfusion rat model: a possible role for NMDARs-mediated synaptic alterations. Nutritional Neuroscience. 2022: 1-13 Wise-Faberowski L et al., J Neurosurg Anesthesiol, 2006, 18(4), 240-246. Wong EH et al., Proc Natl Acad Sci U S A, 1986, 83(18), 7104-7108. Zhou H, Shi H, Li X, et al. Involvement of Cyclin Dependent Kinase 5 in M4 Muscarinic Acetylcholine Receptor-Mediated Cholinergic Transmission within the Mouse Dorsal Striatum[J]. 2021