TargetMol

Enzastaurin

Product Code:
 
TAR-T6280
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6280-5mg5mg£105.00
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Quantity:
TAR-T6280-1mL1 mL * 10 mM (in DMSO)£109.00
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Quantity:
TAR-T6280-10mg10mg£119.00
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Quantity:
TAR-T6280-25mg25mg£141.00
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Quantity:
TAR-T6280-50mg50mg£171.00
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Quantity:
TAR-T6280-100mg100mg£230.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Enzastaurin (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.
CAS:
170364-57-5
Formula:
C32H29N5O2
Molecular Weight:
515.617
Pathway:
Chromatin/Epigenetic; Cytoskeletal Signaling; Autophagy; Apoptosis
Purity:
0.9852
SMILES:
Cn1cc(C2=C(C(=O)NC2=O)c2cn(C3CCN(Cc4ccccn4)CC3)c3ccccc23)c2ccccc12
Target:
Apoptosis; PKC; Autophagy

References

Rovedo MA, et al. J Invest Dermatol, 2011, 131(7), 1442-1449. Podar K, et al. Blood, 2007, 109(4), 1669-1677. Graff JR, et al. Cancer Res, 2005, 65(16), 7462-7469. Feng J, Chen Z, Ma Y, et al. AKAP1 contributes to impaired mtDNA replication and mitochondrial dysfunction in podocytes of diabetic kidney disease. Int J Biol Sci. 2022, 18(10): 4026-4042