TargetMol

KU-0060648

Product Code:
 
TAR-T6557
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6557-1mg1mg£114.00
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Quantity:
TAR-T6557-5mg5mg£168.00
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TAR-T6557-10mg10mg£228.00
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TAR-T6557-25mg25mg£436.00
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TAR-T6557-50mg50mg£598.00
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Quantity:
TAR-T6557-100mg100mg£808.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
CAS:
881375-00-4
Formula:
C33H34N4O4S
Molecular Weight:
582.72
Pathway:
PI3K/Akt/mTOR signaling; DNA Damage/DNA Repair
Purity:
0.9921
SMILES:
CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1
Target:
DNA-PK; PI3K; mTOR

References

Munck JM, et al. Mol Cancer Ther, 2012, 11(8), 1789-1798. Celine Cano, et al. Mol Cancer Ther, 2009, 8(12 Suppl), A138.