TargetMol

(S)-(+)-Rolipram

Product Code:
 
TAR-T6649
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6649-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T6649-5mg5mg£117.00
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TAR-T6649-10mg10mg£148.00
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TAR-T6649-25mg25mg£230.00
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TAR-T6649-50mg50mg£378.00
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TAR-T6649-100mg100mg£615.00
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Further Information

Bioactivity:
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
CAS:
85416-73-5
Formula:
C16H21NO3
Molecular Weight:
275.348
Pathway:
Metabolism; Apoptosis
Purity:
0.9971
SMILES:
COc1ccc(cc1OC1CCCC1)[C@H]1CNC(=O)C1
Target:
Apoptosis; PDE

References

Chen TC, et al. Cancer Biol Ther, 2002, 1(3), 268-276. Pon DJ, et al. Cell Biochem Biophys, 1998, 29(1-2), 159-178. Underwood DC, et al. J Pharmacol Exp Ther, 1993, 266(1), 306-313 Souness JE, et al. Br J Pharmacol, 1996, 118(3), 649-658