TargetMol

SB-705498

Product Code:
 
TAR-T6660
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T6660-1mg1mg£95.00
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TAR-T6660-5mg5mg£125.00
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TAR-T6660-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T6660-10mg10mg£172.00
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TAR-T6660-25mg25mg£306.00
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TAR-T6660-50mg50mg£497.00
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TAR-T6660-100mg100mg£687.00
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TAR-T6660-500mg500mg£1,340.00
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This product comes from: United States.
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Further Information

Bioactivity:
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
CAS:
501951-42-4
Formula:
C17H16BrF3N4O
Molecular Weight:
429.241
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
FC(F)(F)c1ccc(nc1)N1CC[C@H](C1)NC(=O)Nc1ccccc1Br
Target:
TRP/TRPV Channel

References

Chen W T, Lin G B, Lin S H, et al. Static magnetic field enhances the anticancer efficacy of capsaicin on HepG2 cells via capsaicin receptor TRPV1[J]. PloS one. 2018 Jan 16;13(1):e0191078. Chen W T, Lin G B, Lin S H, et al. Static magnetic field enhances the anticancer efficacy of capsaicin on HepG2 cells via capsaicin receptor TRPV1. PloS One. 2018 Jan 16;13(1):e0191078 Rami HK, et al. Bioorg Med Chem Lett. 2006, 16(12), 3287-3291. Gunthorpe MJ, et al. J Pharmacol Exp Ther. 2007, 321(3), 1183-1192.