TargetMol

EAI045

Product Code:
 
TAR-T6824
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6824-5mg5mg£99.00
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Quantity:
TAR-T6824-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T6824-10mg10mg£114.00
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Quantity:
TAR-T6824-25mg25mg£138.00
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Quantity:
TAR-T6824-50mg50mg£172.00
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Quantity:
TAR-T6824-100mg100mg£237.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
CAS:
1942114-09-1
Formula:
C19H14FN3O3S
Molecular Weight:
383.4
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; JAK/STAT signaling
Purity:
0.9973
SMILES:
Oc1ccc(F)cc1C(N1Cc2ccccc2C1=O)C(=O)Nc1nccs1
Target:
EGFR

References

Jia Y, et al. Nature. 2016, 534(7605):129-32. Wang S, et al. J Hematol Oncol. 2016, 9(1):59.