TargetMol

NSC 228155

Product Code:
 
TAR-T6908
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6908-5mg5mg£105.00
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Quantity:
TAR-T6908-1mL1 mL * 10 mM (in DMSO)£109.00
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Quantity:
TAR-T6908-10mg10mg£119.00
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TAR-T6908-25mg25mg£173.00
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Quantity:
TAR-T6908-50mg50mg£256.00
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Quantity:
TAR-T6908-100mg100mg£393.00
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Quantity:
TAR-T6908-200mg200mg£489.00
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Quantity:
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Further Information

Bioactivity:
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
CAS:
113104-25-9
Formula:
C11H6N4O4S
Molecular Weight:
290.25
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Chromatin/Epigenetic; JAK/STAT signaling
Purity:
0.9984
SMILES:
[O-][N+](=O)c1ccc(Sc2cccc[n+]2[O-])c2nonc12
Target:
EGFR; Epigenetic Reader Domain; DNA/RNA Synthesis; Histone Acetyltransferase

References

Sakanyan V, et al. Sci Rep. 2016, 6:21088. Sakanyan V, et al. Sci Rep. 2014, 4:3977. Xie F, et al. Bioorg Med Chem Lett. 2013, 23(19):5371-5.