TargetMol

RHPS4

Product Code:
 
TAR-T6967
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6967-5mg5mg£102.00
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Quantity:
TAR-T6967-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T6967-10mg10mg£122.00
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TAR-T6967-25mg25mg£172.00
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TAR-T6967-50mg50mg£262.00
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Quantity:
TAR-T6967-100mg100mg£389.00
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This product comes from: United States.
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Further Information

Bioactivity:
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
CAS:
390362-78-4
Formula:
C23H20F2N2O4S
Molecular Weight:
458.48
Pathway:
Apoptosis; DNA Damage/DNA Repair
Purity:
0.9859
SMILES:
COS([O-])(=O)=O.Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23
Target:
Apoptosis; Telomerase

References

Gao C, Deng J, Anwar N, et al.Molecular crowding promotes the aggregation of parallel structured G-quadruplexes.International Journal of Biological Macromolecules.2023: 124442. Salvati E, et al. J Clin Invest. 2007, 117(11):3236-47. Phatak P, et al. Br J Cancer. 2007, 96(8):1223-33. Wang Z, Deng J, Umer M, et al. RHPS4 shifted the conformation ensemble equilibrium of Tel24 by preferentially stabilizing the (3+ 1) hybrid-2 conformation. RSC Advances. 2022, 12(40): 26011-26015.