TargetMol

Vitexin

Product Code:
 
TAR-T6S1369
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S1369-5mg5mg£109.00
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TAR-T6S1369-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T6S1369-10mg10mg£136.00
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TAR-T6S1369-25mg25mg£205.00
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TAR-T6S1369-50mg50mg£273.00
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TAR-T6S1369-100mg100mg£374.00
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This product comes from: United States.
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Further Information

Bioactivity:
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis signaling pathways.
CAS:
3681-93-4
Formula:
C21H20O10
Molecular Weight:
432.381
Pathway:
oxidation-reduction
Purity:
0.9964
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1
Target:
Antioxidant

References

Can ?D1, Demir ?zkay ?, ??el U?.. Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms[J]. European Journal of Pharmacology, 2013, 699(1-3):250-257. Jang S A, Hwang Y H, Yang H, et al. Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis. Biomedicine & Pharmacotherapy. 2022, 147: 112640. Jung M A, Song H K, Jo K, et al.Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.Biomedicine & Pharmacotherapy.2023, 161: 114482.