TargetMol

N-Formyl-Met-Leu-Phe

Product Code:
 
TAR-T7091
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7091-5mg5mg£111.00
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Quantity:
TAR-T7091-10mg10mg£125.00
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Quantity:
TAR-T7091-25mg25mg£165.00
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Quantity:
TAR-T7091-50mg50mg£221.00
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Quantity:
TAR-T7091-100mg100mg£296.00
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Quantity:
TAR-T7091-200mg200mg£409.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
CAS:
59880-97-6
Formula:
C21H31N3O5S
Molecular Weight:
437.56
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Target:
TNF

References

Lad P M , Olson C V , Smiley P A . Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin.[J]. Proceedings of the National Academy of Sciences, 1985, 82(3):869-873. Shin M K , Jang Y H , Yoo H J , et al. N-Formyl-Methionyl-Leucyl-Phenylalanine (fMLP) Promotes Osteoblast Differentiation via the N-Formyl Peptide Receptor 1-mediated Signaling Pathway in Human Mesenchymal Stem Cells from Bone Marrow[J]. Journal of Biological Chemistry, 2011, 286(19):17133-17143. Zhan Y, Chen Q, Song Y, et al. Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells. Cell Biology and Toxicology. 2022: 1-21