TargetMol

DC260126

Product Code:
 
TAR-T7127
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7127-5mg5mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7127-1mL1 mL * 10 mM (in DMSO)£114.00
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Quantity:
TAR-T7127-10mg10mg£124.00
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TAR-T7127-25mg25mg£186.00
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Quantity:
TAR-T7127-50mg50mg£253.00
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This product comes from: United States.
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Further Information

Bioactivity:
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
CAS:
346692-04-4
Formula:
C16H18FNO2S
Molecular Weight:
307.38
Pathway:
GPCR/G Protein; Apoptosis; Endocrinology/Hormones
Purity:
0.98
SMILES:
CCCCc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1
Target:
Apoptosis; GPR

References

Peng S , Ting W , Yuren Z , et al. DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic ?-Cells Dysfunction in db/db Mice[J]. PLoS ONE, 2013, 8(6):e66744-. Zhang X , Yan G , Li Y , et al. DC260126, a small-molecule antagonist of GPR40, improves insulin tolerance but not glucose tolerance in obese Zucker rats[J]. Biomedicine and Pharmacotherapy, 2010, 64(9):0-651.