TargetMol

XY1

Product Code:
 
TAR-T7157
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7157-2mg2mg£96.00
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TAR-T7157-5mg5mg£111.00
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TAR-T7157-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T7157-10mg10mg£142.00
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TAR-T7157-25mg25mg£209.00
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TAR-T7157-50mg50mg£328.00
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TAR-T7157-100mg100mg£497.00
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TAR-T7157-500mg500mg£994.00
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This product comes from: United States.
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Further Information

Bioactivity:
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as a negative control for SGC707 in studies involving PRMT3 action.
CAS:
1624117-53-8
Formula:
C17H19N3O2
Molecular Weight:
297.358
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
O=C(CNC(=O)Nc1ccc2ccccc2c1)N1CCCC1
Target:
Histone Methyltransferase

References

Kaniskan, H. ?mit, Szewczyk M M , Yu Z , et al. A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase?3 (PRMT3)[J]. Angewandte Chemie, 2015, 127(17):5255-5259. B?rsting C, Tomas C, Morling N.SNP typing of the reference materials SRM 2391b 1-10, K562, XY1, XX74, and 007 with the SNPforID multiplex[J].Forensic Sci Int Genet. 2011 Jun;5(3):e81-2. Sontakke SD1, Kandukuri LR, Umapathy G,et al.The 34,XY1,der(13) chromosome constitution with loss of Y2 is associated with unilateral testicular hypoplasia in the endangered Indian blackbuck antelope (Antilope cervicapra).Sex Dev. 2012;6(5):240-6.