TargetMol

Lofexidine

Product Code:
 
TAR-T7160
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7160-1mL1 mL * 10 mM (in DMSO)£95.00
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TAR-T7160-5mg5mg£95.00
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TAR-T7160-50mg50mg£139.00
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This product comes from: United States.
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Further Information

Bioactivity:
Lofexidine is a selective α2-receptor agonist, Lofexidine reduces narcotic withdrawal symptoms.
CAS:
31036-80-3
Formula:
C11H12Cl2N2O
Molecular Weight:
259.13
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9908
SMILES:
CC(Oc1c(Cl)cccc1Cl)C1=NCCN1
Target:
Adrenergic Receptor

References

Gorodetzky CW, Walsh SL, Martin PR,et al.A phase III, randomized, multi-center, double blind, placebo controlled study of safety and efficacy of lofexidine for relief of symptoms in individuals undergoing inpatient opioid withdrawal[J].Drug Alcohol Depend. 2017 Jul 1;176:79-88. Pergolizzi J V , Annabi H , Gharibo C , et al. The Role of Lofexidine in Management of Opioid Withdrawal[J]. Pain and Therapy, 2018.