TargetMol

TPPU

Product Code:
 
TAR-T7199
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7199-5mg5mg£124.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7199-1mL1 mL * 10 mM (in DMSO)£130.00
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TAR-T7199-10mg10mg£164.00
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TAR-T7199-25mg25mg£261.00
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TAR-T7199-50mg50mg£389.00
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Quantity:
TAR-T7199-100mg100mg£544.00
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This product comes from: United States.
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Further Information

Bioactivity:
TPPU is a potent inhibitor of both human and mouse sEH (IC50 of 3.7 and 2.8 nM, respectively)
CAS:
1222780-33-7
Formula:
C16H20F3N3O3
Molecular Weight:
359.349
Pathway:
Metabolism
Purity:
0.98
SMILES:
CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1
Target:
Epoxide Hydrolase

References

Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys[J]. British Journal of Pharmacology, 2012, 165. Yao ES, Tang Y, Liu XH,et al.TPPU protects tau from H2O2-induced hyperphosphorylation in HEK293/tau cells by regulating PI3K/AKT/GSK-3? pathway[J].J Huazhong Univ Sci Technolog Med Sci. 2016 Dec;36(6):785-790.