TargetMol

Pyrvinium pamoate

Product Code:
 
TAR-T7333
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7333-5mg5mg£95.00
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TAR-T7333-10mg10mg£109.00
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TAR-T7333-1mL1 mL * 10 mM (in DMSO)£113.00
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TAR-T7333-25mg25mg£122.00
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TAR-T7333-50mg50mg£136.00
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TAR-T7333-100mg100mg£167.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pyrvinium pamoate is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug due to its inhibition of Wnt/β-catenin pathway in some types of cancer.
CAS:
3546-41-6
Formula:
C75H70N6O6
Molecular Weight:
1151.421
Pathway:
Stem Cells; Cytoskeletal Signaling
Purity:
0.9843
SMILES:
CN(C)c1ccc2[n+](C)c(C=Cc3cc(C)n(c3C)-c3ccccc3)ccc2c1.CN(C)c1ccc2[n+](C)c(C=Cc3cc(C)n(c3C)-c3ccccc3)ccc2c1.Oc1c(cc2ccccc2c1Cc1c(O)c(cc2ccccc12)C([O-])=O)C([O-])=O
Target:
Wnt/beta-catenin

References

Xu F , Zhu Y , Lu Y , et al. Anthelmintic pyrvinium pamoate blocks Wnt/?-catenin and induces apoptosis in multiple myeloma cells[J]. Oncology Letters, 2018. Zheng L , Liu Y , Pan J . Inhibitory effect of pyrvinium pamoate on uveal melanoma cells involves blocking of Wnt/?-catenin pathway[J].2017(49):898.