TargetMol

TCN238

Product Code:
 
TAR-T7494
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7494-5mg5mg£112.00
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Quantity:
TAR-T7494-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T7494-10mg10mg£142.00
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TAR-T7494-25mg25mg£220.00
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TAR-T7494-50mg50mg£328.00
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Quantity:
TAR-T7494-100mg100mg£516.00
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This product comes from: United States.
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Further Information

Bioactivity:
TCN 238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).
CAS:
125404-04-8
Formula:
C12H11N3
Molecular Weight:
197.24
Pathway:
Neuroscience
Purity:
0.98
SMILES:
Nc1nccc(/C=C/c2ccccc2)n1
Target:
GluR

References

Pershina E V , Arkhipov V I . Subacute activation of mGlu4 receptors causes the feedback inhibition of its gene expression in rat brain[J]. Life Sciences, 2016, 153:50-54. East S P , Bamford S , Dietz M G A , et al. An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 20(16):4901-4905.