TargetMol

Cyclo(his-pro)

Product Code:
 
TAR-T7511
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7511-1mg1mg£95.00
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TAR-T7511-5mg5mg£128.00
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TAR-T7511-10mg10mg£168.00
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TAR-T7511-25mg25mg£262.00
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TAR-T7511-50mg50mg£425.00
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TAR-T7511-100mg100mg£592.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway.
CAS:
53109-32-3
Formula:
C11H14N4O2
Molecular Weight:
234.259
Pathway:
Metabolism; NF-κb
Purity:
0.9987
SMILES:
O=C1NC(Cc2cnc[nH]2)C(=O)N2CCCC12
Target:
NF-κB; Endogenous Metabolite

References

Bellezza I , Grottelli S , Mierla A L , et al. Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity[J]. The International Journal of Biochemistry & Cell Biology, 2014, 51:159-169. Minelli A , Grottelli S , Mierla A , et al. Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-?B and Nrf2 signalling[J]. International Journal of Biochemistry & Cell Biology, 2012, 44(3):0-535.