TargetMol

BMS-191011

Product Code:
 
TAR-T7512
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T7512-5mg5mg£111.00
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TAR-T7512-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T7512-10mg10mg£134.00
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TAR-T7512-25mg25mg£201.00
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TAR-T7512-50mg50mg£318.00
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TAR-T7512-100mg100mg£442.00
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Further Information

Bioactivity:
BMS-191011 is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
CAS:
202821-81-6
Formula:
C16H10ClF3N2O3
Molecular Weight:
370.71
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Oc1ccc(Cl)cc1Cn1nc(oc1=O)-c1ccc(cc1)C(F)(F)F
Target:
Potassium Channel

References

Hewawasam P . Synthesis of water-soluble prodrugs of BMS-191011: a maxi-K channel opener targeted for post-stroke neuroprotection.[J]. Bioorganic & Medicinal Chemistry Letters, 2003, 13(10):1695-1698. Mori A , Suzuki S , Sakamoto K , et al. BMS-191011, an Opener of Large-Conductance Ca2+-Activated Potassium Channels, Dilates Rat Retinal Arterioles in Vivo[J]. Biological & Pharmaceutical Bulletin, 2011, 34(1):150-152.